GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UCEC | cis | rs2241437 | 1 | rs12328085 | chr2:86262009 | LOC90784 | chr2:86247339-86250991:- | -0.69 | -6.44 | 1.51E-9 | Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) |
| UCEC | cis | rs12590640 | 1 | rs12435273 | chr14:36852104 | MBIP | chr14:36767764-36789882:- | 0.36 | 4.65 | 7.28E-6 | Malaria |
| UCEC | cis | rs12590640 | 1 | rs12435930 | chr14:36865731 | MBIP | chr14:36767764-36789882:- | 0.37 | 4.76 | 4.55E-6 | Malaria |
| UCEC | cis | rs10935120 | 1 | rs12490835 | chr3:134223730 | ANAPC13 | chr3:134196547-134204865:- | 0.4 | 4.63 | 7.74E-6 | Height |
| UCEC | cis | rs12590640 | 1 | rs12588304 | chr14:36854180 | MBIP | chr14:36767764-36789882:- | 0.36 | 4.52 | 1.22E-5 | Malaria |
| UCEC | cis | rs12590640 | 1 | rs12590991 | chr14:36872910 | MBIP | chr14:36767764-36789882:- | 0.36 | 4.53 | 1.18E-5 | Malaria |
| UCEC | cis | rs6542095 | 1 | rs12612788 | chr2:113555296 | PSD4 | chr2:113931560-113960676:+ | -0.47 | -4.43 | 1.8E-5 | Endometriosis |
| UCEC | cis | rs2241437 | 1 | rs12622009 | chr2:86248325 | LOC90784 | chr2:86247339-86250991:- | -0.69 | -6.44 | 1.51E-9 | Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) |
| UCEC | cis | rs9815354 | 1 | rs12639255 | chr3:41861738 | ULK4 | chr3:41288091-42003660:- | 0.45 | 5.21 | 6.03E-7 | Diastolic blood pressure |
| UCEC | cis | rs6534441 | 1 | rs12651542 | chr4:125419479 | ANKRD50 | chr4:125585468-125633887:- | 0.3 | 4.73 | 5.15E-6 | Major depressive disorder |
| UCEC | cis | rs1577917 | 1 | rs12661204 | chr6:86678586 | SNHG5 | chr6:86386726-86388451:- | -0.53 | -5.8 | 3.64E-8 | Response to antipsychotic treatment |
| UCEC | cis | rs1577917 | 1 | rs12663651 | chr6:86701655 | SNHG5 | chr6:86386726-86388451:- | -0.42 | -4.96 | 1.9E-6 | Response to antipsychotic treatment |
| UCEC | cis | rs1577917 | 1 | rs12663690 | chr6:86640162 | SNHG5 | chr6:86386726-86388451:- | 0.45 | 5.37 | 2.92E-7 | Response to antipsychotic treatment |
| UCEC | cis | rs1577917 | 1 | rs12664335 | chr6:86597774 | SNHG5 | chr6:86386726-86388451:- | 0.42 | 5.12 | 9.19E-7 | Response to antipsychotic treatment |
| UCEC | cis | rs1577917 | 1 | rs12665321 | chr6:86769289 | SNHG5 | chr6:86386726-86388451:- | -0.51 | -5.84 | 3.02E-8 | Response to antipsychotic treatment |